Bob Byington’s smart, subversive comedy skips through 35 years in the life of Max Youngman (Keith Poulson), his best (and only) friend Sal (Nick Offerman, “Parks and Recreation”), and the woman they both adore (Jess Weixler, Teeth). As they stumble in and out of hilariously misguided relationships — strung together with animated vignettes by Bob Sabiston (A Scanner Darkly) and an original score by Vampire Weekend’s Chris Baio — Max never ages, holding on to a mysterious briefcase that may or may not contain the secret to life.